201406_New article_ThS Nguyen Minh Hieu

Chúc mừng PGS. TS. Nguyễn Hoàng Hải và ThS. Nguyễn Minh Hiếu, cán bộ Trung tâm Nano và Năng lượng có tên trong bài báo quốc tế mới được nhận đăng.

Tên bài báo: Highly sensitive DNA sensor based on polypyrrole nanowire

Các tác giả: Mai Anh Tuan, Duc Thanh Pham, Thi Xuan Chu, Nguyen Minh Hieu, Nguyen Hoang Hai

Tạp chí: Applied Surface Science

Link DOI: http://dx.doi.org/10.1016/j.apsusc.2014.05.032

Abstract: This paper describes the development of a DNA sensor based on polypyrrole nanowire. By using potentiostatic technique, in the presence of gelatin as the soft mold, the polypyrrole nanowires were synthesized on the surface of the micro-sensor. The surface enhanced Raman spectroscopy shows that the N H ends of the polypyrrole nanowires orientate upward from the surface facilitating the DNA probe immobilization through the simple linkage with the phosphate groups of the probe DNA. The label-free signal readout was carried out by lock-in amplifier technique. The response time of the DNA sensor is 10 s and the measurement time was 5 min. The lowest detectable concentration of Escherichia coli DNA was 0.1 nM.